Deschloroketamine

Deschloroketamine (also known as 2'-Oxo-PCM, DXE, DCK, or Deschloroketamine) is a synthetic dissociative of the arylcyclohexylamine class. It is a research chemical that is often used in scientific and medical research.

Chemistry

Deschloroketamine is an arylcylohexylamine class compound. Arylcyclohexylamines are named for their structures which include a cyclohexane ring bound to an aromatic ring along with an amine group. Deschloroketamine contains a phenyl ring bonded to a cyclohexane ring. An amino methyl chain (-N-CH3) is bound to the same carbon of the cyclohexane ring as the ketone group. Deschloroketamine is a chiral molecule and is often produced as a racemate.

Pharmacology

Deschloroketamine acts primarily as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually the "K-hole" or an intense and unpleasant feeling of dissociation.

Effects

The effects of Deschloroketamine are similar to other dissociative anesthetics such as ketamine and phencyclidine (PCP). These effects include analgesia, anesthesia, hallucinations, and a feeling of disconnection from one's physical body.

Legality

The legality of Deschloroketamine varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.

Safety

As with all substances, the safety of Deschloroketamine depends on various factors including the dose, the user's health, and the context in which it's used. It is recommended that Deschloroketamine be used in a safe, controlled environment, and that users have a sober person present to assist in case of emergencies.

See also

• Dissociative
• Arylcyclohexylamine
• Ketamine
• Phencyclidine