Dibenzylideneacetone
Dibenzylideneacetone (dba) is an organic compound used in organic synthesis as a ligand in organometallic chemistry. It is notable for its role in the Mizoroki-Heck reaction, a method used for the synthesis of organic compounds.
Structure and Properties[edit | edit source]
Dibenzylideneacetone is a yellow crystalline solid with a melting point of 75-77 °C. It is soluble in alcohol and ether, but insoluble in water. The compound is a chelating ligand towards transition metals, forming complexes such as chloro(dimethyl sulfide)gold(I) and palladium(II) complexes.
Synthesis[edit | edit source]
Dibenzylideneacetone can be synthesized by the condensation reaction of benzaldehyde and acetone in the presence of a base such as sodium hydroxide.
Applications[edit | edit source]
Dibenzylideneacetone is used as a ligand in the synthesis of organometallic compounds. It is also used in the Mizoroki-Heck reaction, a palladium-catalyzed carbon-carbon bond forming reaction.
Safety[edit | edit source]
Dibenzylideneacetone may cause eye irritation and skin irritation. It is recommended to handle with care and avoid contact with skin and eyes.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD