Dimethoxybenzene

Dimethoxybenzene is an organic compound with the formula C6H4(OCH3)2. It is a derivative of benzene, with two methoxy groups (-OCH3) attached to the benzene ring in place of two hydrogen atoms.

Structure and Properties

Dimethoxybenzene is a colorless liquid that is slightly soluble in water but readily soluble in organic solvents. It has a pleasant, aromatic odor. The molecule is planar, with the two methoxy groups on opposite sides of the benzene ring. This arrangement is known as the para position in aromatic substitution nomenclature.

Synthesis

Dimethoxybenzene can be synthesized by the Friedel-Crafts alkylation of benzene with dimethyl sulfate in the presence of a Lewis acid catalyst such as aluminium chloride.

Uses

Dimethoxybenzene is used as a solvent and as a starting material in the synthesis of other organic compounds. It is also used in the manufacture of perfumes and flavors, due to its pleasant, aromatic odor.

Safety

Like many organic solvents, dimethoxybenzene is flammable and should be handled with care. It can cause irritation to the skin and eyes, and prolonged exposure can lead to serious health problems.

See Also

• Anisole
• Veratrole
• Methoxybenzene