Divicine

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Divicine[edit | edit source]

Chemical structure of Divicine

Divicine is a naturally occurring compound found in certain legumes, particularly in the seeds of the Vicia faba plant. It is a type of alkaloid and is known for its distinctive red coloration. Divicine is also commonly referred to as "vicine" or "vicin."

Chemical Structure[edit | edit source]

The chemical structure of divicine consists of a pyrimidine ring fused with a pyrazine ring. It also contains a glucose molecule attached to the pyrimidine ring. This unique structure is responsible for the compound's characteristic red color.

Occurrence[edit | edit source]

Divicine is primarily found in the seeds of the Vicia faba plant, commonly known as broad beans or fava beans. It is present in high concentrations in the seeds, especially in the cotyledons. The compound is synthesized by the plant as a defense mechanism against certain pests and pathogens.

Health Effects[edit | edit source]

Divicine has been found to have both beneficial and harmful effects on human health. On one hand, it possesses antioxidant properties and has been associated with potential anti-inflammatory effects. Some studies suggest that divicine may have a protective role against certain chronic diseases, such as cardiovascular diseases and certain types of cancer.

On the other hand, divicine can also have toxic effects when consumed in large quantities or by individuals with a specific genetic condition called "favism." Favism is a hereditary disorder characterized by a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD). In individuals with favism, the consumption of divicine-rich foods, such as fava beans, can lead to a severe hemolytic reaction, causing the destruction of red blood cells.

Culinary Uses[edit | edit source]

Despite its potential health risks, divicine-rich foods like fava beans are consumed in many cultures around the world. In some cuisines, fava beans are a staple ingredient and are used in various dishes, such as soups, stews, salads, and spreads. However, it is important for individuals with G6PD deficiency to avoid consuming divicine-containing foods to prevent adverse reactions.

References[edit | edit source]






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Contributors: Prab R. Tumpati, MD