Dose (biochemistry)

Dose (biochemistry)

The term dose in biochemistry refers to the quantity of a substance that may be absorbed by a living organism or its parts. This can include substances such as chemicals, drugs, or toxins. The dose is usually measured in milligrams (mg) or micrograms (µg).

Definition

In biochemistry, a dose is defined as the amount of a substance that is absorbed by an organism or its parts. This can be a single dose, or it can be a cumulative dose over a period of time. The dose can be delivered in a variety of ways, including through ingestion, inhalation, injection, or skin absorption.

Measurement

The dose is typically measured in milligrams (mg) or micrograms (µg), although other units of measurement may also be used depending on the substance and the context. The dose can also be expressed as a concentration, such as milligrams per liter (mg/L) or micrograms per cubic meter (µg/m³).

Factors Influencing Dose Response

The response of an organism to a dose of a substance can be influenced by a variety of factors. These can include the organism's age, sex, genetic makeup, overall health, and previous exposure to the substance. Other factors can include the route of administration, the duration of exposure, and the presence of other substances.

Dose-Response Relationship

The dose-response relationship is a fundamental concept in biochemistry. It describes the change in effect on an organism caused by differing levels of exposure to a stimulus or stressor. This relationship can be graphically represented by a dose-response curve, which plots the magnitude of the effect against the dose of the substance.

See Also

• Toxicology
• Pharmacology
• Pharmacokinetics
• Pharmacodynamics

References

Dose (biochemistry) Resources
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