Embryoma

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Embryoma
Synonyms Nephroblastoma, Wilms' tumor
Pronounce N/A
Specialty N/A
Symptoms Abdominal mass, abdominal pain, hematuria, hypertension
Complications Metastasis, renal failure
Onset Typically in children aged 3 to 4 years
Duration Variable, depending on treatment
Types N/A
Causes Genetic mutations, including WT1 and WT2 gene mutations
Risks Family history, certain genetic syndromes (e.g., WAGR syndrome, Denys-Drash syndrome, Beckwith-Wiedemann syndrome)
Diagnosis Ultrasound, CT scan, MRI, biopsy
Differential diagnosis Neuroblastoma, Rhabdomyosarcoma, Renal cell carcinoma
Prevention N/A
Treatment Surgery, chemotherapy, radiation therapy
Medication N/A
Prognosis Generally good with treatment, 5-year survival rate > 90% in localized cases
Frequency Approximately 1 in 10,000 children
Deaths N/A


A type of tumor derived from embryonic tissue








Classification
External resources


Embryoma is a type of tumor that originates from embryonic tissue. These tumors are typically found in children and are considered a form of pediatric cancer. Embryomas are characterized by their rapid growth and potential to spread to other parts of the body. They are often classified based on the type of embryonic tissue from which they arise.

Types of Embryoma[edit | edit source]

Embryomas can be classified into several types, depending on the tissue of origin:

Nephroblastoma[edit | edit source]

Also known as Wilms' tumor, nephroblastoma is a common type of embryoma that originates in the kidney. It is most frequently diagnosed in children under the age of five. Symptoms may include abdominal swelling, pain, and blood in the urine.

Hepatoblastoma[edit | edit source]

Hepatoblastoma is a rare embryonic tumor of the liver. It typically occurs in children under the age of three. Symptoms can include abdominal swelling, jaundice, and weight loss.

Neuroblastoma[edit | edit source]

Neuroblastoma is a cancer that arises from immature nerve cells and most commonly affects infants and young children. It often starts in the adrenal glands but can also develop in the neck, chest, abdomen, or spine.

Medulloblastoma[edit | edit source]

Medulloblastoma is a type of embryonic tumor that occurs in the cerebellum, the part of the brain that controls balance and coordination. It is the most common malignant brain tumor in children.

Diagnosis[edit | edit source]

The diagnosis of embryoma typically involves a combination of imaging studies, such as ultrasound, CT scan, or MRI, and a biopsy to examine the tumor cells under a microscope. Blood tests may also be conducted to look for specific markers associated with certain types of embryomas.

Treatment[edit | edit source]

Treatment for embryoma depends on the type and stage of the tumor. Common treatment options include:

  • Surgery: Surgical removal of the tumor is often the first step in treatment.
  • Chemotherapy: Drugs are used to kill cancer cells or stop them from growing.
  • Radiation therapy: High-energy rays are used to target and destroy cancer cells.

The treatment plan is usually tailored to the individual patient, taking into account the type of embryoma, its location, and the overall health of the child.

Prognosis[edit | edit source]

The prognosis for children with embryoma varies depending on the type and stage of the tumor at diagnosis. Early detection and treatment are crucial for improving outcomes. Advances in treatment have significantly increased survival rates for many types of embryomas.

Related pages[edit | edit source]

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Contributors: Prab R. Tumpati, MD