Etomethazene

Etomethazene is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the pyrazolone group. It is primarily used for its analgesic and antipyretic properties.

Pharmacology

Etomethazene works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. Prostaglandins play a key role in the body's inflammatory response, and by inhibiting their production, etomethazene can help to reduce inflammation, pain, and fever.

Clinical Use

Etomethazene is used to treat a variety of conditions that cause pain and inflammation, including arthritis, gout, and menstrual pain. It can also be used to reduce fever in patients with conditions such as influenza or pneumonia.

Side Effects

Like all NSAIDs, etomethazene can cause a range of side effects. These can include gastrointestinal problems such as stomach ulcers and bleeding, as well as kidney damage in some patients. It can also cause allergic reactions in some patients, particularly those who are allergic to other NSAIDs.

Contraindications

Etomethazene should not be used in patients with a history of peptic ulcer disease, as it can increase the risk of gastrointestinal bleeding. It should also be used with caution in patients with kidney disease or heart disease, as it can worsen these conditions.

Interactions

Etomethazene can interact with a number of other medications, including anticoagulants, diuretics, and other NSAIDs. It can also interact with alcohol, increasing the risk of gastrointestinal bleeding.

See Also

• Non-steroidal anti-inflammatory drug
• Pyrazolone
• Cyclooxygenase
• Prostaglandin