Etozolin

From WikiMD.com - Food, Medicine & Wellness Encyclopedia

A diuretic drug used in the treatment of hypertension and edema


Chemical structure of Etozolin

Etozolin is a diuretic medication primarily used in the management of hypertension and edema. It belongs to the class of thiazide-like diuretics, which are known for their ability to increase the excretion of sodium and water from the body, thereby reducing blood volume and lowering blood pressure.

Pharmacology[edit | edit source]

Etozolin works by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubules of the nephron in the kidney. This action leads to an increase in the excretion of sodium, chloride, and water, resulting in a diuretic effect. The reduction in blood volume subsequently decreases cardiac output and peripheral vascular resistance, which helps in lowering blood pressure.

Medical Uses[edit | edit source]

Etozolin is indicated for the treatment of:

Side Effects[edit | edit source]

Common side effects of etozolin include:

Less common but more serious side effects can include:

Contraindications[edit | edit source]

Etozolin should not be used in individuals with:

  • Severe renal impairment
  • Anuria (inability to urinate)
  • Known hypersensitivity to etozolin or other thiazide-like diuretics

Mechanism of Action[edit | edit source]

Etozolin acts on the distal convoluted tubule of the nephron, where it inhibits the sodium-chloride symporter. This inhibition prevents the reabsorption of sodium and chloride ions, leading to increased excretion of these ions along with water. The diuretic effect reduces plasma volume, which decreases cardiac output and peripheral resistance, ultimately lowering blood pressure.

Chemical Properties[edit | edit source]

Etozolin is chemically classified as a thiazide-like diuretic. Its molecular structure is similar to that of other thiazide diuretics, but it possesses unique properties that differentiate it from classical thiazides.

Related Pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD