Fenoprofen

Fenoprofen

Fenoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to treat pain, inflammation, and fever. It belongs to the propionic acid class of NSAIDs, which also includes ibuprofen and naproxen. Fenoprofen is marketed under the brand name Nalfon among others.

Pharmacology

Fenoprofen works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals in the body that cause inflammation and pain. By inhibiting COX, fenoprofen reduces the levels of prostaglandins, thereby reducing inflammation and pain.

Clinical Use

Fenoprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis. It is also used to treat mild to moderate pain, including menstrual pain. Fenoprofen is available in capsule form and is usually taken three or four times a day.

Side Effects

Like other NSAIDs, fenoprofen can cause a variety of side effects. The most common side effects include nausea, vomiting, diarrhea, constipation, and stomach pain. More serious side effects can include ulcers, bleeding, and holes in the stomach or intestine. Fenoprofen can also increase the risk of heart attacks and strokes.

Precautions

Before taking fenoprofen, patients should inform their healthcare provider if they are allergic to fenoprofen, aspirin, or other NSAIDs. Patients should also inform their healthcare provider if they have a history of asthma, heart disease, liver disease, or kidney disease.

Interactions

Fenoprofen can interact with several other medications, including blood thinners, diuretics, lithium, and other NSAIDs. It can also interact with alcohol, which can increase the risk of stomach bleeding.

See Also

• Nonsteroidal anti-inflammatory drug
• Cyclooxygenase
• Prostaglandin
• Osteoarthritis
• Rheumatoid arthritis

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