Filenadol

Filenadol is a nonsteroidal anti-inflammatory drug (NSAID) used primarily for its analgesic, antipyretic, and anti-inflammatory properties. It is commonly prescribed for the treatment of pain, fever, and inflammation associated with various medical conditions.

Mechanism of Action

Filenadol works by inhibiting the activity of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are responsible for the synthesis of prostaglandins, which are lipid compounds that play a key role in the mediation of inflammation, pain, and fever. By reducing the production of prostaglandins, filenadol helps to alleviate these symptoms.

Indications

Filenadol is indicated for the management of:

• Osteoarthritis
• Rheumatoid arthritis
• Dysmenorrhea
• Acute pain
• Chronic pain
• Fever

Dosage and Administration

The dosage of filenadol varies depending on the condition being treated, the severity of symptoms, and the patient's response to the medication. It is typically administered orally in the form of tablets or capsules. The usual adult dose ranges from 200 mg to 400 mg, taken every 4 to 6 hours as needed. It is important to follow the prescribing physician's instructions and not to exceed the recommended dose.

Side Effects

Common side effects of filenadol include:

• Gastrointestinal discomfort
• Nausea
• Dizziness
• Headache

Serious side effects, although rare, may include:

• Gastrointestinal bleeding
• Ulceration
• Renal impairment
• Hepatotoxicity
• Allergic reactions

Contraindications

Filenadol is contraindicated in patients with:

• Known hypersensitivity to filenadol or other NSAIDs
• History of gastrointestinal bleeding or peptic ulcer disease
• Severe renal impairment
• Severe hepatic impairment
• Pregnancy (especially in the third trimester)

Drug Interactions

Filenadol may interact with other medications, including:

• Anticoagulants
• Antihypertensive drugs
• Diuretics
• Other NSAIDs
• Corticosteroids

Precautions

Patients should use filenadol with caution if they have a history of:

• Cardiovascular disease
• Hypertension
• Asthma
• Kidney disease
• Liver disease

See Also

• Nonsteroidal anti-inflammatory drug
• Pain management
• Inflammation
• Analgesic