Fluorocholine

Fluorocholine (also known as 18F-fluorocholine, FCH, or fluoromethylcholine) is a radiopharmaceutical used in medical imaging. It is a choline analog where the hydrogen atom is replaced by the radioisotope fluorine-18. Fluorocholine is used in positron emission tomography (PET) imaging to detect cancer and other diseases.

Chemistry

Fluorocholine is a choline analog, meaning it has a similar structure to choline but with one key difference: one of the hydrogen atoms in choline is replaced by fluorine-18, a radioisotope. This modification allows fluorocholine to be used in PET imaging.

Medical uses

Fluorocholine is used in PET imaging to detect diseases such as cancer. It is particularly useful in detecting prostate cancer, as the cancer cells take up choline to a greater extent than normal cells. By using fluorocholine, doctors can see where the cancer cells are in the body and how active they are.

Production

Fluorocholine is produced by substituting a hydrogen atom in choline with fluorine-18. This is done using a nuclear reactor and a process called nuclear transmutation.

See also

• Choline
• Fluorine-18
• Positron emission tomography
• Prostate cancer

Fluorocholine Resources
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