Flupentixol/melitracen

Flupentixol/Melitracen is a combination of two psychotropic drugs, flupentixol and melitracen. It is used in the treatment of various psychiatric disorders such as depression, anxiety, and neurotic conditions.

Composition[edit | edit source]

The combination drug contains two active ingredients: flupentixol, a thioxanthene derivative, and melitracen, a tricyclic antidepressant (TCA). Flupentixol is a typical antipsychotic that works by blocking dopamine receptors in the brain, while melitracen is an antidepressant that increases the levels of certain chemicals in the brain that help elevate mood.

Indications[edit | edit source]

Flupentixol/melitracen is indicated for the treatment of emotional instability accompanied by depression, anxiety, apathy, or sleep disturbances. It is also used in the management of neurotic depression, reactive depression, and adjustment disorders.

Side Effects[edit | edit source]

Common side effects of flupentixol/melitracen include drowsiness, dry mouth, constipation, and blurred vision. In rare cases, it may cause extrapyramidal symptoms such as tremors, rigidity, and bradykinesia.

Contraindications[edit | edit source]

Flupentixol/melitracen is contraindicated in patients with known hypersensitivity to either flupentixol or melitracen. It should not be used in patients with cardiac disorders, liver disease, renal impairment, or glaucoma. It is also contraindicated in patients with a history of seizures or manic episodes.

Interactions[edit | edit source]

Flupentixol/melitracen may interact with other medications, including other antidepressants, antipsychotics, antihistamines, and anticholinergics. It may also interact with alcohol, leading to increased drowsiness and sedation.

Dosage and Administration[edit | edit source]

The dosage of flupentixol/melitracen is individualized based on the patient's condition and response to treatment. It is usually taken orally, once or twice daily.