Fluperolone

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Fluperolone is a synthetic glucocorticoid corticosteroid used in the treatment of various inflammatory and allergic conditions. It is known for its potent anti-inflammatory and immunosuppressive properties.

Pharmacology

Fluperolone works by inhibiting the release of substances in the body that cause inflammation. It binds to glucocorticoid receptors, which leads to the suppression of the immune system and a reduction in the production of inflammatory mediators such as cytokines and prostaglandins.

Medical Uses

Fluperolone is primarily used to treat conditions such as:

• Allergic reactions
• Asthma
• Rheumatoid arthritis
• Dermatitis
• Inflammatory bowel disease

Side Effects

Common side effects of fluperolone include:

• Weight gain
• Hypertension
• Osteoporosis
• Hyperglycemia
• Increased risk of infection

Contraindications

Fluperolone should not be used in patients with:

• Systemic fungal infections
• Known hypersensitivity to fluperolone or any of its components

Mechanism of Action

Fluperolone exerts its effects by modulating the expression of genes involved in the inflammatory response. It decreases the synthesis of pro-inflammatory cytokines and increases the production of anti-inflammatory proteins.

Dosage

The dosage of fluperolone varies depending on the condition being treated and the patient's response to therapy. It is important to follow the prescribing physician's instructions carefully.

See Also

• Glucocorticoid
• Corticosteroid
• Anti-inflammatory
• Immunosuppressive drug