Flurbiprofen
A nonsteroidal anti-inflammatory drug
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Overview[edit | edit source]
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is commonly prescribed for conditions such as arthritis, dental pain, and postoperative pain. Flurbiprofen works by inhibiting the production of prostaglandins, which are chemicals in the body responsible for inflammation and pain.
Pharmacology[edit | edit source]
Flurbiprofen is a member of the propionic acid class of NSAIDs, which also includes drugs like ibuprofen and naproxen. It is available in both oral and topical formulations. The drug is absorbed in the gastrointestinal tract and is metabolized in the liver. Its mechanism of action involves the inhibition of the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are involved in the synthesis of prostaglandins.
Medical Uses[edit | edit source]
Flurbiprofen is used to manage various types of pain and inflammation. It is effective in treating:
- Osteoarthritis and rheumatoid arthritis
- Ankylosing spondylitis
- Dysmenorrhea (painful menstruation)
- Migraine
- Postoperative pain
Side Effects[edit | edit source]
Common side effects of flurbiprofen include:
Serious side effects may include:
Contraindications[edit | edit source]
Flurbiprofen should not be used in individuals with:
Interactions[edit | edit source]
Flurbiprofen may interact with other medications, including:
Related pages[edit | edit source]
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