Fluticasone
Fluticasone is a synthetic glucocorticoid used to treat various inflammatory and allergic conditions. It is available in several forms, including inhalers, nasal sprays, and topical creams. Fluticasone is commonly prescribed for conditions such as asthma, allergic rhinitis, and dermatitis.
Medical Uses[edit | edit source]
Fluticasone is used in the management of several conditions:
- Asthma: Fluticasone inhalers are used as a preventive treatment to reduce inflammation and prevent asthma attacks.
- Allergic rhinitis: Fluticasone nasal sprays help alleviate symptoms such as nasal congestion, sneezing, and runny nose.
- Dermatitis: Topical fluticasone creams are used to reduce inflammation and itching in various skin conditions.
Mechanism of Action[edit | edit source]
Fluticasone works by binding to the glucocorticoid receptor, which leads to the suppression of inflammatory mediators. This action reduces inflammation and immune responses, providing relief from symptoms associated with allergic and inflammatory conditions.
Side Effects[edit | edit source]
Common side effects of fluticasone include:
- Nasal irritation or dryness (when used as a nasal spray)
- Oral thrush (when used as an inhaler)
- Skin irritation (when used topically)
Serious side effects are rare but can include adrenal suppression and osteoporosis with long-term use.
Pharmacokinetics[edit | edit source]
Fluticasone has a high first-pass metabolism, which limits its systemic availability when administered via inhalation or nasal spray. It is metabolized primarily in the liver and excreted in the urine and feces.
Forms and Dosage[edit | edit source]
Fluticasone is available in various forms:
- Inhalers: Used for asthma and chronic obstructive pulmonary disease (COPD).
- Nasal sprays: Used for allergic rhinitis.
- Topical creams: Used for skin conditions like dermatitis and eczema.
The dosage and form depend on the condition being treated and the patient's response to the medication.
History[edit | edit source]
Fluticasone was first approved for medical use in the early 1990s. It has since become a widely used medication for managing inflammatory and allergic conditions.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD