Gestrinone

Gestrinone is a hormone that is used in the treatment of endometriosis, a condition where the tissue that normally lines the inside of the uterus grows outside of it. It is a synthetic steroid with strong antiprogestogenic and antiestrogenic effects, and weak androgenic properties.

Mechanism of Action

Gestrinone works by interacting with progesterone and estrogen receptors in the body. It inhibits the growth of endometrial tissue by suppressing the production of these hormones. This leads to a reduction in the size and number of endometrial implants, and a decrease in the associated pain.

Uses

Gestrinone is primarily used in the treatment of endometriosis. It may also be used in the treatment of fibroids, benign tumors that grow in or on the uterus.

Side Effects

Common side effects of gestrinone include acne, oily skin, weight gain, and changes in menstrual bleeding patterns. Less common side effects include nausea, headache, and breast tenderness.

Contraindications

Gestrinone should not be used in women who are pregnant or breastfeeding, or in those with liver disease or unexplained vaginal bleeding.

See Also

• Endometriosis
• Hormone
• Steroid
• Progesterone
• Estrogen
• Fibroids

Gestrinone Resources
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