Giant-cell fibroblastoma

Giant-cell fibroblastoma
Synonyms
Pronounce	N/A
Specialty	Oncology, Dermatology
Symptoms	Painless skin nodule
Complications	N/A
Onset	Childhood
Duration
Types
Causes	Unknown
Risks
Diagnosis	Histopathology
Differential diagnosis	Dermatofibrosarcoma protuberans, Fibrosarcoma
Prevention
Treatment	Surgical excision
Medication
Prognosis	Generally good with complete excision
Frequency	Rare
Deaths

Giant-cell fibroblastoma is a rare, benign, soft tissue tumor that typically occurs in children and young adults. It is characterized by the presence of large, multinucleated cells (giant cells) and fibroblasts, which are cells that produce collagen and other structural fibers.

Clinical Presentation

Patients with giant-cell fibroblastoma often present with a painless, slow-growing mass. The tumor is most commonly found in the deep soft tissues of the extremities, but can also occur in the trunk, head, and neck.

Diagnosis

Diagnosis of giant-cell fibroblastoma is typically made through a combination of clinical examination, imaging studies, and histopathological examination of a biopsy specimen. The tumor is characterized by the presence of large, multinucleated cells (giant cells) and fibroblasts.

Treatment

Treatment for giant-cell fibroblastoma typically involves surgical removal of the tumor. In some cases, radiation therapy may be used as an adjunct to surgery. The prognosis for patients with giant-cell fibroblastoma is generally good, with a low rate of recurrence following complete surgical resection.

See Also

• Fibroblast
• Soft tissue tumor
• Radiation therapy