Fibrosarcoma
A type of cancer that develops from fibrous connective tissue
Overview[edit | edit source]
Fibrosarcoma is a malignant tumor that arises from fibroblasts, the cells responsible for producing collagen and other fibers. It is a type of soft tissue sarcoma and can occur in any part of the body, although it is most commonly found in the extremities, trunk, and head and neck region.
Pathophysiology[edit | edit source]
Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The histological appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.
Clinical Presentation[edit | edit source]
Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the lungs and other organs.
Diagnosis[edit | edit source]
The diagnosis of fibrosarcoma is typically made through a combination of imaging studies and biopsy. Imaging techniques such as MRI and CT scan are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.
Treatment[edit | edit source]
The primary treatment for fibrosarcoma is surgical resection with wide margins to ensure complete removal of the tumor. In some cases, radiation therapy and/or chemotherapy may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.
Prognosis[edit | edit source]
The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.
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Contributors: Prab R. Tumpati, MD
