Malignant peripheral nerve sheath tumor

Malignant peripheral nerve sheath tumor (MPNST) is a rare form of cancer that originates from the peripheral nerve sheath, the protective layer that surrounds nerves. These tumors are often aggressive and can spread to other parts of the body.

Symptoms

The symptoms of MPNST can vary depending on the location of the tumor. Common symptoms include a growing lump or mass, pain or discomfort, and neurological problems such as numbness or weakness.

Causes

The exact cause of MPNST is unknown, but it is often associated with certain genetic conditions such as Neurofibromatosis type 1 (NF1) and Schwannomatosis.

Diagnosis

Diagnosis of MPNST typically involves a combination of physical examination, imaging tests such as MRI or CT scan, and biopsy.

Treatment

Treatment for MPNST often involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells.

Prognosis

The prognosis for MPNST varies depending on factors such as the size and location of the tumor, the patient's overall health, and the success of treatment.

See also

• Neurofibromatosis
• Schwannoma
• Sarcoma

References

Malignant peripheral nerve sheath tumor Resources
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