Granulomatous

Granulomatous is a term used in medicine to describe a type of inflammation that is characterized by the formation of granulomas. Granulomas are small nodules of immune cells that form in response to chronic inflammation, often in response to an infection or foreign substance.

Causes

Granulomatous inflammation can be caused by a variety of conditions, including infections, autoimmune diseases, and certain types of cancer. Some of the most common causes include:

• Tuberculosis: This is a bacterial infection that primarily affects the lungs, but can also affect other parts of the body. It is one of the most common causes of granulomatous inflammation.
• Sarcoidosis: This is an inflammatory disease that can affect any organ in the body, but most often affects the lungs and lymph nodes.
• Crohn's disease: This is a type of inflammatory bowel disease that can cause granulomas to form in the digestive tract.
• Vasculitis: This is a group of disorders that cause inflammation of the blood vessels, which can lead to the formation of granulomas.

Symptoms

The symptoms of granulomatous inflammation can vary widely depending on the underlying cause and the organs affected. Some common symptoms may include:

• Fever
• Fatigue
• Weight loss
• Cough
• Shortness of breath
• Skin rash
• Joint pain

Diagnosis

Diagnosis of granulomatous inflammation typically involves a combination of medical history, physical examination, and laboratory tests. Imaging studies such as X-rays or CT scans may be used to identify granulomas in the body. In some cases, a biopsy may be needed to confirm the diagnosis and identify the cause of the inflammation.

Treatment

Treatment for granulomatous inflammation depends on the underlying cause. For infections, antibiotics or antiviral medications may be used. For autoimmune diseases, treatment may involve medications to suppress the immune system and reduce inflammation. In some cases, surgery may be needed to remove granulomas or affected tissue.

See also

• Granuloma
• Inflammation
• Tuberculosis
• Sarcoidosis
• Crohn's disease
• Vasculitis

Granulomatous Resources
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