C-reactive protein
<languages /><translate> C-reactive protein (224 aa, ~25 kda) is an acute phase reactant and encoded by the human crp gene. This protein is cleaved during biological activation and is associated with host defense mechanisms and inflammatory responses.
CRP as a marker of inflammation[edit | edit source]
C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection.
Other names[edit | edit source]
- C-reactive protein, serum
- CRP
Conditions used[edit | edit source]
A CRP test may be used in a wide range of conditions to find or monitor conditions that cause inflammation. These include:
- Bacterial infections, such as sepsis, a severe and sometimes life-threatening condition
- Fungal infection
- Inflammatory bowel disease, a disorder that causes swelling and bleeding in the intestines
- An autoimmune disorder such as lupus or rheumatoid arthritis
- An infection of the bone called osteomyelitis
Nomal values[edit | edit source]
- Thenormal CRP reading is less than 10 milligram per liter (mg/L).
- A test result showing a CRP level of more than 10 mg/L is a sign of serious infection, trauma or chronic disease
- If your results show a high level of CRP, it probably means you have some type of inflammation in your body.
- A CRP test doesn't explain the cause or location of the inflammation.
CRP and hsCRP[edit | edit source]
- A CRP test is sometimes confused with a high-sensitivity-(hs) CRP test.
- Although they both measure CRP, they are used to diagnose different conditions.
- Recent evidence also suggests that CRP levels may have value in identifying individuals at greater risk of a heart attack.
hsCRP normal levels[edit | edit source]
A high-sensitivity CRP (hs-CRP) test measures low levels of CRP using laser nephelometry. The test gives results in 25 minutes with a sensitivity down to 0.04 mg/L. The risk of developing cardiovascular disease is quantified as follows:
- low: hs-CRP level under 1.0 mg/L (low risk of cardiovascular disease)
- average: between 1.0 and 3.0 mg/L (medium risk)
- high: above 3.0 mg/L (high risk)
See also[edit | edit source]
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