HOXC11
HOXC11 is a gene that belongs to the homeobox family of genes. The protein encoded by this gene is a transcription factor that plays a crucial role in the development and growth of certain tissues and organs in the body.
Function[edit | edit source]
The HOXC11 gene is part of the HOX gene family, a group of genes that are essential for the proper development of the body. These genes encode proteins that bind to specific regions of DNA and help control the activity of other genes. As a result, they play a key role in determining the body's basic structure, including the number and types of limbs and the shape of internal organs.
In particular, the HOXC11 gene is known to be involved in the development of the limbs and the reproductive system. It is expressed in the uterus and ovaries in females, and in the testes in males.
Clinical significance[edit | edit source]
Mutations in the HOXC11 gene have been associated with several health conditions. For example, they have been linked to endometriosis, a painful condition in which tissue similar to the lining of the uterus grows outside of the uterus. Mutations in this gene may also increase the risk of certain types of cancer, including ovarian cancer and breast cancer.
Research[edit | edit source]
Research into the HOXC11 gene is ongoing, with scientists seeking to better understand its role in development and disease. This research could potentially lead to new treatments for conditions associated with mutations in this gene.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
