HOXC5
HOXC5 is a gene that belongs to the homeobox family of genes. The HOXC5 gene provides instructions for making a protein that plays a crucial role in the development of cells and tissues during early embryonic development. This protein is a transcription factor, which means it attaches (binds) to specific regions of DNA and helps control the activity of particular genes.
Function[edit | edit source]
The HOXC5 gene is part of a larger family of homeobox genes, which act during early embryonic development to control the formation of body structures. Specifically, the HOXC5 protein is involved in the development of the vertebral column, the series of small bones that make up the spine.
Clinical Significance[edit | edit source]
Mutations in the HOXC5 gene have been associated with several types of cancer, including breast cancer and leukemia. These mutations can lead to the production of a HOXC5 protein that does not function properly, which can disrupt normal cell growth and division and lead to the formation of a tumor.
Research[edit | edit source]
Research is ongoing to better understand the role of the HOXC5 gene in development and disease. Scientists are studying the effects of HOXC5 mutations in cells and animal models to learn more about how this gene contributes to cancer development.
See Also[edit | edit source]
References[edit | edit source]
Genes on human chromosome 12 | ||||
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This human chromosome 12 related article is a stub.
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