HU6

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HU6


HU-6 is a synthetic cannabinoid from the HU-210 series with analgesic properties. It was developed by the team led by Raphael Mechoulam at the Hebrew University of Jerusalem in the late 1980s.

Chemistry[edit | edit source]

HU-6 is a member of the HU series of cannabinoids, which are named after the Hebrew University of Jerusalem where they were first synthesized. The chemical structure of HU-6 is similar to that of other cannabinoids in the HU series, such as HU-210 and HU-211. It is a lipophilic compound, which means it is soluble in fats and oils.

Pharmacology[edit | edit source]

The pharmacological effects of HU-6 are primarily due to its action on the cannabinoid receptors in the brain. It is a potent agonist at the CB1 receptor, which is the same receptor that is activated by the main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC).

HU-6 has been shown to have analgesic properties, meaning it can relieve pain. This makes it a potential candidate for the development of new pain relief medications. However, like other cannabinoids, it also has psychoactive effects, which can limit its medical use.

Research and Potential Uses[edit | edit source]

Research into the potential uses of HU-6 is ongoing. Due to its analgesic properties, it is being investigated for use in the treatment of chronic pain conditions. However, the psychoactive effects of HU-6, similar to those of THC, can limit its use in a medical context.

Legal Status[edit | edit source]

The legal status of HU-6 varies by country. In some jurisdictions, it is classified as a controlled substance due to its psychoactive effects. In others, it is legal for use in research but not for recreational or medical use.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD