Incadronic acid
Incadronic acid (INN, trade name Bisphonal) is a type of bisphosphonate, a class of drugs that prevent the loss of bone density. Bisphosphonates are used to treat diseases such as osteoporosis, Paget's disease, and bone metastases.
Etymology[edit | edit source]
The term "Incadronic acid" is derived from the chemical name of the compound, which is a type of bisphosphonate. The prefix "Inca" may refer to the Inca civilization, known for their advanced knowledge in many fields including medicine. The suffix "dronic acid" is common in the nomenclature of bisphosphonates, indicating the presence of two phosphonate groups in the molecule.
Pharmacology[edit | edit source]
Incadronic acid, like other bisphosphonates, works by binding to hydroxyapatite in bone tissue, preventing the action of osteoclasts, the cells that break down bone. This helps to maintain bone density and strength.
Clinical uses[edit | edit source]
Incadronic acid is used in the treatment of various bone-related conditions, including osteoporosis, Paget's disease, and bone metastases associated with certain types of cancer. It may also be used to treat hypercalcemia (high calcium levels in the blood) caused by malignancy.
Side effects[edit | edit source]
Common side effects of Incadronic acid include gastrointestinal problems such as nausea, abdominal pain, and constipation. More serious side effects can include osteonecrosis of the jaw and atypical femoral fractures.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
