Iproclozide

Iproclozide is a monoamine oxidase inhibitor (MAOI) and antidepressant that was previously used in Europe but was withdrawn from the market due to it causing liver damage. It is structurally related to iproniazid.

Pharmacology

Iproclozide is a reversible inhibitor of monoamine oxidase (MAO), an enzyme that breaks down neurotransmitters such as serotonin, norepinephrine, and dopamine. By inhibiting MAO, iproclozide increases the levels of these neurotransmitters in the brain, which can help to alleviate symptoms of depression.

Side Effects

The most serious side effect of iproclozide is hepatotoxicity, or liver damage. This led to its withdrawal from the market. Other side effects can include nausea, dizziness, and insomnia.

History

Iproclozide was developed in the 1960s as a treatment for depression. It was used in Europe for several years before being withdrawn from the market due to concerns about liver damage.

See Also

• Monoamine oxidase inhibitor
• Antidepressant
• Iproniazid

Iproclozide Resources
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