L-Norpseudoephedrine

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L-Norpseudoephedrine.svg

L-Norpseudoephedrine is a stimulant drug of the phenethylamine and amphetamine chemical classes. It is an isomer of norpseudoephedrine, which is also known as cathine. L-Norpseudoephedrine is structurally related to ephedrine and pseudoephedrine, which are commonly used as decongestants and bronchodilators.

Chemical Structure and Properties

L-Norpseudoephedrine has the chemical formula C9H13NO and a molecular weight of 151.21 g/mol. It is a chiral compound, meaning it has a specific stereochemistry and exists in different enantiomers. The "L" in L-Norpseudoephedrine denotes the specific enantiomer of the compound.

Pharmacology

L-Norpseudoephedrine acts as a central nervous system stimulant. It increases the release of norepinephrine and dopamine in the brain, leading to increased alertness, reduced fatigue, and enhanced physical performance. It is less potent than amphetamine but shares similar pharmacological effects.

Medical Uses

L-Norpseudoephedrine is not commonly used in modern medicine. However, its isomer, cathine, is found in the leaves of the khat plant and has been used traditionally in some cultures for its stimulant effects. Ephedrine and pseudoephedrine, related compounds, are used in the treatment of nasal congestion and asthma.

Legal Status

The legal status of L-Norpseudoephedrine varies by country. In many places, it is regulated due to its potential for abuse and its structural similarity to other controlled stimulants like amphetamine.

Side Effects

The side effects of L-Norpseudoephedrine can include increased heart rate, elevated blood pressure, insomnia, anxiety, and nervousness. Long-term use or abuse can lead to more serious health issues, including cardiovascular problems and addiction.

See Also

• Ephedrine
• Pseudoephedrine
• Cathine
• Amphetamine
• Stimulant