Norpseudoephedrine

Norpseudoephedrine, also known as phenylpropanolamine (PPA), is a psychoactive drug of the amphetamine chemical class that is used as a stimulant, decongestant, and anorectic. It is commonly found in over-the-counter cold and allergy medications.

Chemistry[edit | edit source]

Norpseudoephedrine is a stereoisomer of ephedrine. It is a chiral compound, and is used in the form of its racemic mixture. The compound is a member of the amphetamine family and shares many of the family's properties, including stimulant effects.

Medical uses[edit | edit source]

Norpseudoephedrine is used as a decongestant and anorectic. As a decongestant, it works by constricting (shrinking) blood vessels (veins and arteries) in the body. This reduces the blood flow to certain areas and allows nasal and respiratory passages to open up. As an anorectic, it is used to suppress appetite in the short-term treatment of obesity.

Side effects[edit | edit source]

Common side effects of norpseudoephedrine include nausea, vomiting, dizziness, and headache. More serious side effects may include high blood pressure, rapid heart rate, and stroke.

Regulation[edit | edit source]

In many countries, including the United States, norpseudoephedrine is regulated due to its potential for abuse and health risks. It is listed as a Schedule III controlled substance under the Controlled Substances Act in the United States.