LSIL

LSIL or Low-grade Squamous Intraepithelial Lesion is a term used in Pap smear results to describe abnormal growth of squamous cells on the surface of the cervix. LSIL is usually caused by a HPV infection, particularly types 6 and 11, which are considered low-risk for progression to cervical cancer.

Causes

The primary cause of LSIL is an infection with the HPV. There are over 100 types of HPV, but types 6 and 11 are most commonly associated with LSIL. These types are considered low-risk for progression to cervical cancer, but they can cause genital warts and mild cervical changes.

Diagnosis

LSIL is typically diagnosed through a Pap smear, a screening test used to detect precancerous and cancerous processes in the cervix. If LSIL is detected, a colposcopy may be performed for further examination. During a colposcopy, a special magnifying instrument is used to examine the cervix for signs of disease.

Treatment

Treatment for LSIL is usually not necessary, as the majority of cases resolve on their own without intervention. However, regular follow-up Pap smears are recommended to monitor for changes. In some cases, if the LSIL does not resolve or if it progresses, treatment may be necessary. This can include procedures to remove the abnormal cells, such as a LEEP procedure or a cold knife cone biopsy.

See also

• High-grade squamous intraepithelial lesion
• Cervical intraepithelial neoplasia
• Cervical cancer
• Human papillomavirus

LSIL Resources
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