Lascufloxacin
Lascufloxacin is a type of antibiotic that belongs to the fluoroquinolone class. It is primarily used in the treatment of bacterial infections, specifically those caused by gram-positive bacteria.
Mechanism of Action[edit | edit source]
Lascufloxacin works by inhibiting the DNA gyrase and topoisomerase IV, two essential enzymes involved in bacterial DNA replication, transcription, repair, and recombination. By inhibiting these enzymes, lascufloxacin prevents the bacteria from replicating, thereby stopping the infection from spreading.
Uses[edit | edit source]
Lascufloxacin is used to treat a variety of bacterial infections, including pneumonia, bronchitis, sinusitis, and skin infections. It is particularly effective against gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae.
Side Effects[edit | edit source]
Like all antibiotics, lascufloxacin can cause side effects. These may include nausea, vomiting, diarrhea, and abdominal pain. In rare cases, it can cause more serious side effects, such as tendon rupture, neuropathy, and QT prolongation.
Precautions[edit | edit source]
Before taking lascufloxacin, patients should inform their healthcare provider if they have a history of allergy to fluoroquinolones, kidney disease, or heart disease. It is also important to avoid taking lascufloxacin with certain medications, as they can interact and cause adverse effects.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD