Leukocyte esterase

Leukocyte Esterase

Microscopic examination of urine, a common method to detect leukocyte esterase.

Leukocyte Esterase is an enzyme present in white blood cells (leukocytes). It is commonly used in medical diagnostics as an indicator of infection or inflammation, particularly in the urinary tract.

Biochemical Properties

Leukocyte esterase is an enzyme that hydrolyzes esters, a type of chemical compound. It is produced by neutrophils, a type of white blood cell, and plays a role in the body's immune response to infection.

Clinical Significance

The presence of leukocyte esterase in urine is a key marker for urinary tract infections (UTIs) or other inflammatory processes affecting the urinary system.

Detection Methods

A urinalysis dipstick test, used to detect leukocyte esterase.

Leukocyte esterase is commonly detected using a dipstick test during urinalysis. The test strip changes color in the presence of the enzyme, indicating the potential presence of an infection.

Interpretation of Test Results

A positive leukocyte esterase test typically suggests the presence of white blood cells in the urine, which may indicate a UTI or other infection. Further diagnostic tests, such as urine culture or microscopic examination, may be required to confirm the infection and identify the causative organism.

External Links

• Mayo Clinic Labs - Leukocyte Esterase
• MedlinePlus - Urine Test (Urinalysis)

Leukocyte esterase Resources
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