Leukocyte esterase

Leukocyte Esterase[edit | edit source]

Microscopic examination of urine, a common method to detect leukocyte esterase.

Leukocyte Esterase is an enzyme present in white blood cells (leukocytes). It is commonly used in medical diagnostics as an indicator of infection or inflammation, particularly in the urinary tract.

Biochemical Properties[edit | edit source]

Leukocyte esterase is an enzyme that hydrolyzes esters, a type of chemical compound. It is produced by neutrophils, a type of white blood cell, and plays a role in the body's immune response to infection.

Clinical Significance[edit | edit source]

The presence of leukocyte esterase in urine is a key marker for urinary tract infections (UTIs) or other inflammatory processes affecting the urinary system.

Detection Methods[edit | edit source]

A urinalysis dipstick test, used to detect leukocyte esterase.

Leukocyte esterase is commonly detected using a dipstick test during urinalysis. The test strip changes color in the presence of the enzyme, indicating the potential presence of an infection.

Interpretation of Test Results[edit | edit source]

A positive leukocyte esterase test typically suggests the presence of white blood cells in the urine, which may indicate a UTI or other infection. Further diagnostic tests, such as urine culture or microscopic examination, may be required to confirm the infection and identify the causative organism.

External Links[edit | edit source]

Leukocyte esterase Resources
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