Levoamphetamine

Levoamphetamine is a psychostimulant known to increase wakefulness and focus. It is a stereoisomer of the amphetamine class. Levoamphetamine is the levorotatory stereoisomer of amphetamine, the dextrorotatory isomer being dextroamphetamine.

Pharmacology

Levoamphetamine is a releasing agent of norepinephrine, dopamine, and serotonin. It also acts as a reuptake inhibitor for these neurotransmitters. The pharmacodynamics of levoamphetamine are not fully understood, but it is known to have a higher affinity for norepinephrine than for dopamine or serotonin.

Medical Uses

Levoamphetamine is used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD), narcolepsy, and obesity. It is also used off-label for its cognitive enhancing properties, and to help with weight loss.

Side Effects

Common side effects of levoamphetamine include insomnia, dry mouth, loss of appetite, anxiety, nervousness, and mood changes. More serious side effects can include cardiovascular problems, psychosis, and dependence.

See Also

• Amphetamine
• Dextroamphetamine
• Methamphetamine
• Phenethylamine

References

Levoamphetamine Resources
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