Levonorgestrel acetate
Levonorgestrel acetate is a synthetic progestogen used in various contraceptive methods. It is a derivative of 19-nortestosterone and is also known as 17α-acetoxy-18-methyl-19-nor-δ4-testosterone.
Chemistry[edit | edit source]
Levonorgestrel acetate is a synthetic progestogen, specifically a 17α-alkylated 19-nortestosterone derivative. It is structurally related to other 19-nortestosterone progestogens such as norgestrel and norgestimate.
Pharmacology[edit | edit source]
Levonorgestrel acetate acts primarily by preventing ovulation through the suppression of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It also increases the thickness of the cervical mucus, which inhibits sperm penetration and reduces the likelihood of fertilization.
Clinical use[edit | edit source]
Levonorgestrel acetate is used in a variety of contraceptive methods, including intrauterine devices (IUDs), contraceptive implants, and oral contraceptive pills. It is also used in emergency contraception.
Side effects[edit | edit source]
Common side effects of levonorgestrel acetate include nausea, breast tenderness, headache, and changes in menstrual bleeding patterns. Less common side effects include mood changes, weight gain, and acne.
See also[edit | edit source]
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