Lipoatrophic diabetes
Lipoatrophic diabetes (also known as Lawrence Syndrome) is a rare form of diabetes characterized by the loss of adipose tissue, insulin resistance, and hypertriglyceridemia. This condition is also associated with hepatomegaly and acanthosis nigricans.
Symptoms[edit | edit source]
The symptoms of lipoatrophic diabetes include:
Causes[edit | edit source]
The exact cause of lipoatrophic diabetes is unknown. However, it is believed to be associated with autoimmune diseases, infections, and genetic disorders.
Diagnosis[edit | edit source]
Diagnosis of lipoatrophic diabetes is based on clinical features, laboratory tests, and imaging studies. Laboratory tests may include blood glucose levels, lipid profile, and liver function tests. Imaging studies may include ultrasound of the liver and magnetic resonance imaging (MRI) of the abdomen.
Treatment[edit | edit source]
Treatment of lipoatrophic diabetes involves managing the symptoms and preventing complications. This may include insulin therapy, dietary modifications, and exercise. In severe cases, liposuction or fat transplantation may be considered.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
