List of drugs: An–Ap

List of drugs: An–Ap is a comprehensive catalog within the broader scope of pharmacology, detailing a selection of medications and compounds ranging from "An" to "Ap". This list encompasses a variety of pharmaceutical drugs, each with distinct therapeutic uses, chemical structures, and regulatory statuses. The drugs listed here are used in various branches of medicine, including but not limited to anesthesiology, cardiology, psychiatry, and oncology. This article aims to provide an overview of these drugs, highlighting their applications, mechanisms of action, and any relevant pharmacokinetic properties.

List of Drugs: An–Ap[edit | edit source]

Anastrozole[edit | edit source]

Anastrozole, marketed under the brand name Arimidex among others, is a medication used in the treatment of breast cancer. It is specifically indicated for post-menopausal women and works by inhibiting the enzyme aromatase, leading to a reduction in estrogen production which is often a contributing factor in the growth of breast cancer cells.

Andexanet alfa[edit | edit source]

Andexanet alfa, sold under the brand name Andexxa, is an antidote for the anticoagulants rivaroxaban and apixaban, which are frequently used to prevent and treat blood clots. It acts by binding to these anticoagulants, negating their effect and reducing the risk of bleeding complications during emergencies.

Apixaban[edit | edit source]

Apixaban, branded as Eliquis, is an anticoagulant used for the prevention of strokes and blood clots in patients with nonvalvular atrial fibrillation, and for the treatment and prevention of deep vein thrombosis and pulmonary embolism. It works by inhibiting Factor Xa, an important component of the blood clotting cascade.

Aprepitant[edit | edit source]

Aprepitant, known by the brand name Emend, is used in the prevention of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV). It functions as a neurokinin-1 (NK1) receptor antagonist, blocking the action of substance P in the brain, which is a neurotransmitter involved in vomiting.