Lixivaptan

From WikiMD.com - Food, Medicine & Wellness Encyclopedia

Lixivaptan


Lixivaptan is a vasopressin receptor antagonist used in the treatment of hyponatremia (low blood sodium levels) associated with conditions like congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). It is developed by Cardiokine Inc., a biopharmaceutical company focused on the discovery and development of new treatments for cardiovascular diseases.

Mechanism of Action[edit | edit source]

Lixivaptan works by blocking the action of vasopressin, a hormone that regulates the body's water balance. It specifically targets the vasopressin V2 receptor, which is primarily found in the kidneys. By blocking this receptor, Lixivaptan increases the excretion of water in the urine, thereby increasing the concentration of sodium in the blood.

Clinical Trials[edit | edit source]

Lixivaptan has undergone several clinical trials to evaluate its safety and efficacy. In a Phase III clinical trial, Lixivaptan was shown to be effective in correcting hyponatremia in patients with heart failure and SIADH. However, the drug has not yet received approval from the Food and Drug Administration (FDA).

Side Effects[edit | edit source]

Common side effects of Lixivaptan include dry mouth, thirst, and increased urination. In some cases, it may also cause a rapid increase in blood sodium levels, which can lead to serious complications such as osmotic demyelination syndrome.

See Also[edit | edit source]



This medication related article is a stub. You can help WikiMD by expanding it.

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP1 injections from $125 and up biweekly

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.

Why choose W8MD?

Book Your Appointment

Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia and visit Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD