Lymphomatoid granulomatosis
Lymphomatoid granulomatosis (also known as LYG or LG) is a rare lymphoproliferative disorder characterized by lymphoma-like symptoms. It is associated with Epstein-Barr virus (EBV) infection and is considered a form of angiocentric lymphoma.
Epidemiology[edit | edit source]
Lymphomatoid granulomatosis is a rare disease, with an estimated incidence of less than 1 in 1,000,000. It affects both sexes equally and can occur at any age, although it is most common in middle-aged adults.
Pathophysiology[edit | edit source]
The disease is characterized by an abnormal proliferation of B cells that are infected with the Epstein-Barr virus. These cells infiltrate the lungs, skin, kidney, central nervous system and other organs, causing inflammation and damage.
Clinical Presentation[edit | edit source]
Patients with lymphomatoid granulomatosis typically present with nonspecific symptoms such as fever, weight loss, cough, and shortness of breath. Skin lesions, neurological symptoms, and kidney problems may also occur.
Diagnosis[edit | edit source]
Diagnosis of lymphomatoid granulomatosis is based on clinical symptoms, imaging studies, and biopsy of affected tissues. The presence of EBV-infected B cells in the biopsy sample is a key diagnostic feature.
Treatment[edit | edit source]
Treatment options for lymphomatoid granulomatosis include chemotherapy, radiation therapy, and immunotherapy. The choice of treatment depends on the severity of the disease and the patient's overall health.
Prognosis[edit | edit source]
The prognosis of lymphomatoid granulomatosis is variable, with some patients achieving long-term remission while others experience rapid disease progression.
See Also[edit | edit source]
Lymphomatoid granulomatosis Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Bonnu, Prab R. Tumpati, MD