Lynestrenol phenylpropionate

Lynestrenol phenylpropionate is a synthetic, steroidal progestin that was developed and used for medical purposes but is no longer marketed. It is an ester of lynestrenol, a progestogen which has been used in oral contraceptives.

Chemistry

Lynestrenol phenylpropionate, also known as 17α-ethynyl-19-nortestosterone 3-cyclopentyl enol ether phenylpropionate, is a synthetic estrane steroid and a derivative of testosterone. It is more specifically a derivative of nandrolone (19-nortestosterone) and is a member of the estrane group, as well as an analogue of lynestrenol, where a phenylpropionate ester has been added at the C3 position.

Pharmacology

As a progestin, lynestrenol phenylpropionate is a synthetic analogue of progesterone, a natural hormone which regulates the menstrual cycle and plays important roles in pregnancy. Lynestrenol phenylpropionate acts by binding to and activating the progesterone receptor, thereby exerting its progestational activity.

History

Lynestrenol phenylpropionate was developed and introduced for medical use in the 1960s. However, it is no longer marketed and hence is no longer available for use.

See also

• List of progestogen esters
• List of progestins