Eumycetoma

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(Redirected from Maduromycosis)

Eumycetoma is a chronic infection caused by various types of fungi or bacteria. It is characterized by a large number of small nodules on the skin, which can develop into larger abscesses and ulcers. The disease is most common in tropical and subtropical regions, particularly in rural areas where people walk barefoot.

Causes[edit | edit source]

Eumycetoma is caused by a variety of fungi and bacteria that are found in the soil and plant material. The most common causative organisms are the fungi Madurella mycetomatis, Leptosphaeria senegalensis, and Acremonium falciforme, and the bacteria Actinomadura madurae, Nocardia brasiliensis, and Streptomyces somaliensis. The disease is usually contracted through a minor injury or puncture wound, which allows the organisms to enter the body.

Symptoms[edit | edit source]

The main symptom of eumycetoma is the presence of small nodules under the skin, which can develop into larger abscesses and ulcers. These lesions are typically painless, but can cause significant disfigurement and disability. Other symptoms may include swelling, inflammation, and discharge of a grainy material from the lesions.

Diagnosis[edit | edit source]

Diagnosis of eumycetoma is based on the clinical symptoms, as well as laboratory tests. These tests may include a biopsy of the affected tissue, culture of the causative organism, and imaging studies such as X-rays or MRI.

Treatment[edit | edit source]

Treatment of eumycetoma involves a combination of surgery and long-term antifungal or antibacterial therapy. The choice of medication depends on the type of organism causing the infection. In severe cases, amputation of the affected limb may be necessary.

Prevention[edit | edit source]

Prevention of eumycetoma involves avoiding barefoot walking in areas where the disease is common, and prompt treatment of any minor injuries or puncture wounds.


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Contributors: Prab R. Tumpati, MD