Malignant fibrous histiocytoma

Malignant fibrous histiocytoma (MFH) is a type of cancer that develops in the soft tissue. It is also known as undifferentiated pleomorphic sarcoma, particularly when it occurs in the dermis. MFH is the most common type of soft tissue sarcoma in adults.

Symptoms

The symptoms of MFH can vary depending on the location of the tumor. Common symptoms include a noticeable lump or swelling, pain (if the tumor is pressing against nerves or muscles), and inflammation.

Causes

The exact cause of MFH is unknown. However, it is believed to be related to certain genetic mutations. Some cases have been associated with exposure to radiation or certain chemicals.

Diagnosis

Diagnosis of MFH typically involves a combination of physical examination, imaging tests (such as MRI or CT scan), and biopsy. The diagnosis can be confirmed by a pathologist through microscopic examination of the biopsy sample.

Treatment

Treatment for MFH usually involves surgery to remove the tumor. This may be followed by radiation therapy or chemotherapy to kill any remaining cancer cells. In some cases, targeted therapies may be used.

Prognosis

The prognosis for MFH depends on a number of factors, including the size and location of the tumor, the stage of the cancer, and the patient's overall health.

See also

• Soft tissue sarcoma
• Cancer
• Radiation therapy
• Chemotherapy

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