Malum perforans

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Malum perforans (also known as a trophic ulcer, or neurotrophic ulcer) is a long-lasting, usually painless ulcer that penetrates deep into or through the skin, usually on the bottom of the foot, associated with neurological and metabolic disorders, including diabetes mellitus, tabes dorsalis, and leprosy.[1]

Symptoms[edit | edit source]

The main symptom of malum perforans is the presence of skin ulcers, usually on the bottom of the foot. These ulcers are typically painless and can penetrate deep into or through the skin.

Causes[edit | edit source]

Malum perforans is associated with several neurological and metabolic disorders. These include:

  • Diabetes: High blood sugar levels can damage nerves over time, leading to neuropathy and the development of malum perforans.
  • Tabes dorsalis: This is a form of neurosyphilis, which can cause nerve damage and lead to the development of malum perforans.
  • Leprosy: This infectious disease can cause nerve damage and skin ulcers, leading to malum perforans.

Treatment[edit | edit source]

Treatment for malum perforans focuses on managing the underlying condition causing the ulcers. This may involve:

  • Blood sugar control for diabetes
  • Antibiotics for tabes dorsalis or leprosy
  • Wound care for the ulcers, including cleaning and dressing the wound, and off-loading pressure from the ulcerated area.

See also[edit | edit source]

References[edit | edit source]

Malum perforans Resources
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Contributors: Prab R. Tumpati, MD