Mandelic acid
Overview of mandelic acid
Mandelic Acid[edit | edit source]
Mandelic acid is an aromatic alpha hydroxy acid (AHA) with the formula C_H_CH(OH)CO_H. It is a white crystalline solid that is soluble in water and polar organic solvents. Mandelic acid is used in various applications, including as an intermediate in the synthesis of other compounds and in cosmetic products for its exfoliating properties.
Structure and Properties[edit | edit source]
Mandelic acid consists of a benzene ring with a carboxylic acid group and a hydroxyl group attached to the alpha carbon. This structure gives it both acidic and alcohol-like properties. The presence of the hydroxyl group classifies it as an alpha hydroxy acid, which is known for its ability to promote exfoliation of the skin.
Synthesis[edit | edit source]
Mandelic acid can be synthesized through several methods. One common method involves the hydrolysis of mandelonitrile, which is derived from the reaction of benzaldehyde with hydrogen cyanide. The hydrolysis of mandelonitrile yields mandelic acid and ammonia.
Another method involves the oxidation of phenylglycine using potassium permanganate or other oxidizing agents. This process converts the amino acid into the corresponding alpha hydroxy acid.
Applications[edit | edit source]
Mandelic acid is widely used in the pharmaceutical and cosmetic industries. In cosmetics, it is valued for its ability to improve skin texture and tone by promoting the shedding of dead skin cells. It is often used in chemical peels and other skin care products.
In the pharmaceutical industry, mandelic acid serves as an intermediate in the synthesis of various drugs. Its derivatives are used in the production of antibiotics and other therapeutic agents.
Safety and Handling[edit | edit source]
Mandelic acid should be handled with care, as it can cause irritation to the skin and eyes. Appropriate personal protective equipment (PPE) such as gloves and goggles should be worn when handling the compound.
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