Matricin

Matricin is a naturally occurring chemical compound found in the chamomile plant. It is a sesquiterpene lactone, a class of organic compounds that are known for their various biological activities. Matricin is particularly noted for its anti-inflammatory properties.

Chemical Structure and Properties

Matricin has the molecular formula C15H18O3 and a molecular weight of 246.30 g/mol. It is a sesquiterpene lactone, which means it is a 15-carbon compound derived from three isoprene units. Sesquiterpene lactones are known for their diverse range of biological activities, including anti-inflammatory, anti-microbial, and anti-cancer properties.

Sources

The primary natural source of matricin is the chamomile plant (Matricaria chamomilla). It is found in the flower heads of the plant, along with other bioactive compounds such as apigenin, bisabolol, and chamazulene. Matricin is particularly abundant in the essential oil extracted from chamomile flowers.

Biological Activity

Matricin exhibits significant anti-inflammatory activity. It is thought to inhibit the production of prostaglandins, which are compounds that play a key role in the inflammatory response. This makes matricin, and chamomile extracts containing it, potentially useful in the treatment of conditions characterized by inflammation.

In addition to its anti-inflammatory properties, matricin has also been found to exhibit anti-microbial activity. It has been shown to be effective against a range of bacteria and fungi, including Staphylococcus aureus and Candida albicans.

Medical Uses

Due to its anti-inflammatory and anti-microbial properties, matricin has potential applications in medicine. It is often used in traditional medicine as a component of chamomile tea or essential oil, which are used to treat a variety of ailments including digestive problems, skin conditions, and anxiety.

Safety and Toxicity

While matricin is generally considered safe when used in moderation, excessive consumption can lead to allergic reactions in some individuals. Symptoms can include skin rashes, eye irritation, and, in severe cases, anaphylaxis.

See Also

• Chamomile
• Sesquiterpene lactones
• Prostaglandins