Mazapertine

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Mazapertine is a atypical antipsychotic that is currently under development. It is a dopamine receptor partial agonist, with selectivity for the D2, D3, and D4 subtypes.

Pharmacology[edit | edit source]

Mazapertine acts as a partial agonist at dopamine receptors, specifically the D2, D3, and D4 subtypes. This means that it can both activate these receptors and block them, depending on the circumstances. This is in contrast to full agonists, which only activate receptors, and antagonists, which only block them.

Development[edit | edit source]

Mazapertine is currently under development as a potential treatment for schizophrenia and other psychotic disorders. It is being developed by the pharmaceutical company Pfizer.

Clinical Trials[edit | edit source]

As of now, Mazapertine has undergone several phases of clinical trials. These trials are designed to test the safety and efficacy of the drug in treating schizophrenia and other psychotic disorders. The results of these trials are not yet available.

See Also[edit | edit source]

Mazapertine Resources
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Contributors: Prab R. Tumpati, MD