Meralluride

Meralluride is a diuretic and antihypertensive agent. It is a mercurial diuretic. Meralluride is also known by its trade name, Mersalyl. It is used in the treatment of hypertension and edema.

Pharmacology

Meralluride works by inhibiting the reabsorption of sodium and chloride in the kidney's proximal tubule and loop of Henle. This increases the excretion of water, sodium, chloride, and other electrolytes, thereby increasing urine output and reducing fluid accumulation in the body.

Side Effects

Like other mercurial diuretics, meralluride can cause several side effects. These include nephrotoxicity, hypokalemia, and hyponatremia. Long-term use can lead to mercury poisoning.

Contraindications

Meralluride is contraindicated in patients with severe renal impairment, as it can worsen kidney function. It is also contraindicated in patients with hypokalemia or hyponatremia, as it can exacerbate these conditions.

See Also

• Diuretic
• Antihypertensive drug
• Mercurial diuretic
• Hypertension
• Edema

Meralluride Resources
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