Metamfepramone

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Metamfepramone is a stimulant drug that belongs to the phenethylamine and amphetamine chemical classes. It is known for its use as an anorectic agent, which means it is used to suppress appetite.

Chemical Structure and Properties[edit | edit source]

Metamfepramone, also known as dimethylcathinone, has a chemical structure similar to that of cathinone, a naturally occurring stimulant found in the khat plant. The chemical formula for metamfepramone is C11H15NO, and it has a molecular weight of 177.24 g/mol.

Pharmacology[edit | edit source]

Metamfepramone acts primarily as a norepinephrine and dopamine reuptake inhibitor, which leads to increased levels of these neurotransmitters in the brain. This action is responsible for its stimulant and appetite-suppressing effects. The drug has a similar mechanism of action to other stimulants like amphetamine and methylphenidate.

Medical Uses[edit | edit source]

Metamfepramone has been used in the treatment of obesity due to its appetite-suppressing properties. It has also been used to treat conditions such as narcolepsy and attention deficit hyperactivity disorder (ADHD), although its use in these conditions is less common compared to other stimulants.

Side Effects[edit | edit source]

Common side effects of metamfepramone include insomnia, dry mouth, increased heart rate, and elevated blood pressure. Long-term use can lead to dependence and potential cardiovascular issues.

Legal Status[edit | edit source]

The legal status of metamfepramone varies by country. In some regions, it is classified as a controlled substance due to its potential for abuse and dependence.

History[edit | edit source]

Metamfepramone was first synthesized in the early 20th century and has been used in various medical applications since then. However, its use has declined over the years due to the development of newer and safer medications.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD