Methylscopolamine bromide

An anticholinergic medication used to treat peptic ulcers and other conditions

Methylscopolamine bromide

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Chemical structure of Methylscopolamine bromide

Methylscopolamine bromide, also known as methscopolamine, is a quaternary ammonium anticholinergic medication. It is primarily used to treat peptic ulcers and other conditions that involve excessive gastrointestinal secretions and motility.

Pharmacology

Methylscopolamine bromide is a muscarinic antagonist, which means it blocks the action of the neurotransmitter acetylcholine on muscarinic receptors. This action reduces the secretion of gastric acid and decreases gastrointestinal motility, making it useful in the treatment of peptic ulcer disease.

Mechanism of Action

The drug works by competitively inhibiting the binding of acetylcholine to muscarinic receptors in the parasympathetic nervous system. This inhibition leads to a decrease in the activity of the vagus nerve, which is responsible for stimulating gastric acid secretion and gastrointestinal motility.

Clinical Uses

Methylscopolamine bromide is used in the management of several conditions, including:

• Peptic ulcer disease
• Irritable bowel syndrome
• Hyperhidrosis (excessive sweating)

Side Effects

As with other anticholinergic agents, methylscopolamine bromide can cause a range of side effects, including:

• Dry mouth
• Blurred vision
• Urinary retention
• Constipation
• Tachycardia

Contraindications

Methylscopolamine bromide should not be used in individuals with:

• Glaucoma
• Myasthenia gravis
• Obstructive uropathy
• Obstructive gastrointestinal tract disease

Related pages

• Scopolamine
• Anticholinergic
• Peptic ulcer disease