Morniflumate
Morniflumate is a nonsteroidal anti-inflammatory drug (NSAID) that is used in the treatment of pain and inflammation. It is a derivative of flufenamic acid, and is marketed in Italy and Spain.
Pharmacology[edit | edit source]
Morniflumate is a prodrug that is metabolized in the body to N-(2-hydroxyethyl)flufenamic acid, the active form of the drug. This metabolite is a potent inhibitor of cyclooxygenase, the enzyme responsible for the production of prostaglandins, which play a key role in the inflammatory response.
Clinical use[edit | edit source]
Morniflumate is used in the treatment of a variety of conditions associated with pain and inflammation, including rheumatoid arthritis, osteoarthritis, and dysmenorrhea. It is also used to relieve pain and inflammation following surgery or injury.
Side effects[edit | edit source]
Like other NSAIDs, morniflumate can cause a range of side effects. These may include gastrointestinal problems such as stomach ulcers and bleeding, kidney damage, and an increased risk of heart attack and stroke. It can also cause allergic reactions in some people.
See also[edit | edit source]
Morniflumate Resources | ||
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