Mumps virus
Mumps virus is the causative agent of mumps, a highly contagious viral infection that primarily affects the salivary glands, particularly the parotid glands. The virus belongs to the Paramyxoviridae family and is known scientifically as Rubulavirus mumps. Mumps was once a common childhood disease, but the incidence has significantly decreased in countries where the mumps vaccine is part of the routine immunization schedule.
Etiology[edit | edit source]
The mumps virus is a single-stranded, negative-sense RNA virus. It is enveloped, meaning it has a lipid membrane derived from the host cell. The virus is transmitted from person to person through respiratory droplets or direct contact with an infected individual. The virus can also spread through saliva and close personal contact.
Clinical Features[edit | edit source]
Mumps primarily presents with painful swelling of one or more of the salivary glands, usually the parotid glands, leading to the characteristic puffy cheeks and tender, swollen jaw. Other symptoms may include fever, headache, muscle aches, fatigue, and loss of appetite. In some cases, mumps can lead to complications such as orchitis (inflammation of the testicles) in males, oophoritis (inflammation of the ovaries) in females, meningitis, encephalitis, and hearing loss.
Diagnosis[edit | edit source]
Diagnosis of mumps is primarily based on the clinical presentation. Laboratory tests, including the detection of mumps-specific IgM antibodies in the blood or the isolation of the mumps virus from a sample, can confirm the diagnosis.
Prevention[edit | edit source]
The most effective way to prevent mumps is through vaccination. The MMR vaccine (measles, mumps, and rubella) is a live attenuated vaccine that provides immunity against mumps. It is typically administered in two doses during childhood. High vaccination coverage is crucial to prevent outbreaks of mumps.
Treatment[edit | edit source]
There is no specific antiviral treatment for mumps. Management of the disease focuses on relieving symptoms, such as using analgesics for pain and fever, applying warm or cold compresses to reduce gland swelling, and ensuring adequate fluid intake.
Epidemiology[edit | edit source]
Before the introduction of the mumps vaccine, mumps was a common childhood disease worldwide. Since vaccination became widespread, the incidence of mumps has decreased dramatically in vaccinated populations. However, outbreaks can still occur, especially in settings where vaccine coverage is incomplete.
Public Health and Vaccination Policies[edit | edit source]
Public health efforts to control mumps include maintaining high levels of vaccination coverage and surveillance for the disease. In the event of an outbreak, health authorities may recommend additional doses of the MMR vaccine for at-risk populations.
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Contributors: Prab R. Tumpati, MD