N-Methyltryptamine
N-Methyltryptamine[edit | edit source]
N-Methyltryptamine (NMT) is a naturally occurring tryptamine alkaloid. It is a derivative of tryptamine with a methyl group attached to the nitrogen atom of the indole ring. NMT is structurally related to the more well-known compound N,N-Dimethyltryptamine (DMT), differing by the presence of only one methyl group on the nitrogen atom.
Chemical Properties[edit | edit source]
N-Methyltryptamine is a member of the tryptamine family, which are compounds based on the indole structure with a side chain of an ethylamine group. The chemical formula of NMT is C11H14N2, and it has a molecular weight of 174.24 g/mol. The presence of the methyl group on the nitrogen atom makes it a secondary amine.
Occurrence[edit | edit source]
NMT is found in various plant species and is believed to be a trace alkaloid in some psychoactive plants. It is also present in the human body as a trace amine, although its physiological role is not well understood.
Pharmacology[edit | edit source]
The pharmacological properties of N-Methyltryptamine are not as well studied as those of its close relative, DMT. However, it is thought to interact with serotonin receptors in the brain, similar to other tryptamines. The psychoactive effects of NMT are not well documented, and it is not known to be used recreationally to the same extent as DMT.
Biosynthesis[edit | edit source]
In plants, NMT is synthesized from tryptophan through a series of enzymatic reactions. The initial step involves the decarboxylation of tryptophan to form tryptamine, which is then methylated to produce NMT. This process is similar to the biosynthesis of other tryptamine derivatives.
Related Compounds[edit | edit source]
N-Methyltryptamine is closely related to several other tryptamines, including:
These compounds share a common indole structure and are known for their psychoactive properties.
See Also[edit | edit source]
Related Pages[edit | edit source]
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